When practice does not make a perfect - paradoxical learning curve in schizophrenia and bipolar disorder revealed by different serial reaction time task variants

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cris.lastimport.scopus2025-04-08T03:14:32Z
dc.abstract.enIntroduction: Our previous studies identified a paradoxical implicit motor learning curve in schizophrenia (SZ) and bipolar disorder (BD) patients. This study aimed to verify whether those previously observed deficits may be captured by a new version of the ambidextrous serial reaction time task (SRTT), prepared for use in the MRI. Methods: This study involved 186 participants. A total of 97 participants (33 BD, 33 SZ, and 31 healthy controls, HCs) completed the original, unlimited time response variant of SRTT. A total of 90 individuals (30 BD, 30 SZ, and 30 HCs) underwent a newer, limited response time version of this procedure. Results: There was no significant difference in terms of implicit motor learning indices between both limited and unlimited response time SRTT. Compared to HCs, SZ, and BD patients presented decreased indices of implicit motor learning. Both clinical groups showed a paradoxical learning pattern that differed significantly from the HCs. Moreover, in the SZ group, the pattern depended on the hand performing SRTT. Discussion: The limited response time SRTT variant allowed us to replicate the findings of disrupted implicit motor learning in SZ and BD. The use of this paradigm in further neuroimaging studies may help to determine the neuronal underpinnings of this cognitive dysfunction in the abovementioned clinical groups.
dc.affiliationWydział Psychologii, Katowice
dc.contributor.authorChrobak, Adrian Andrzej
dc.contributor.authorSiuda-Krzywicka, Katarzyna
dc.contributor.authorSoltys, Zbigniew
dc.contributor.authorBielak, Sylwia
dc.contributor.authorNowaczek, Dominik
dc.contributor.authorŻyrkowska, Aleksandra
dc.contributor.authorFafrowicz, Magdalena
dc.contributor.authorMarek, Tadeusz
dc.contributor.authorPęcherzewska, Ewa
dc.contributor.authorKużdżał, Jan
dc.contributor.authorStarowicz-Filip, Anna
dc.contributor.authorGorostowicz, Aleksandra
dc.contributor.authorDudek, Dominika
dc.contributor.authorSiwek, Marcin
dc.date.access2023-09-12
dc.date.accessioned2023-12-19T09:58:11Z
dc.date.available2023-12-19T09:58:11Z
dc.date.created2023-08-16
dc.date.issued2023-09-12
dc.description.abstract<jats:sec><jats:title>Introduction</jats:title><jats:p>Our previous studies identified a paradoxical implicit motor learning curve in schizophrenia (SZ) and bipolar disorder (BD) patients. This study aimed to verify whether those previously observed deficits may be captured by a new version of the ambidextrous serial reaction time task (SRTT), prepared for use in the MRI.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>This study involved 186 participants. A total of 97 participants (33 BD, 33 SZ, and 31 healthy controls, HCs) completed the original, unlimited time response variant of SRTT. A total of 90 individuals (30 BD, 30 SZ, and 30 HCs) underwent a newer, limited response time version of this procedure.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>There was no significant difference in terms of implicit motor learning indices between both limited and unlimited response time SRTT. Compared to HCs, SZ, and BD patients presented decreased indices of implicit motor learning. Both clinical groups showed a paradoxical learning pattern that differed significantly from the HCs. Moreover, in the SZ group, the pattern depended on the hand performing SRTT.</jats:p></jats:sec><jats:sec><jats:title>Discussion</jats:title><jats:p>The limited response time SRTT variant allowed us to replicate the findings of disrupted implicit motor learning in SZ and BD. The use of this paradigm in further neuroimaging studies may help to determine the neuronal underpinnings of this cognitive dysfunction in the abovementioned clinical groups.</jats:p></jats:sec>
dc.description.accesstimeafter_publication
dc.description.physical1-11
dc.description.versionfinal_published
dc.description.volume14
dc.identifier.doi10.3389/fpsyt.2023.1238473
dc.identifier.issn1664-0640
dc.identifier.urihttps://share.swps.edu.pl/handle/swps/231
dc.identifier.weblinkhttps://www.frontiersin.org/articles/10.3389/fpsyt.2023.1238473/full
dc.languageen
dc.pbn.affiliationpsychologia
dc.rightsCC-BY
dc.rights.questionYes_rights
dc.rights.urihttps://creativecommons.org/licenses/by/3.0
dc.share.articleOPEN_REPOSITORY
dc.subject.enmotor functions
dc.subject.enmovement disorders
dc.subject.encognition
dc.subject.encerebellum
dc.subject.enprocedural learning
dc.subject.enaffective disorders
dc.subject.ensequence learning
dc.swps.sciencecloudsend
dc.titleWhen practice does not make a perfect - paradoxical learning curve in schizophrenia and bipolar disorder revealed by different serial reaction time task variants
dc.title.journalFrontiers in Psychiatry
dc.typeJournalArticle
dspace.entity.typeArticle