Tracing diurnal differences in brain anatomy with voxel-based morphometry - associations with sleep characteristics
Tracing diurnal differences in brain anatomy with voxel-based morphometry - associations with sleep characteristics
StatusVoR
Alternative title
Authors
Zaręba, Michał Rafał
Fafrowicz, Magdalena
Marek, Tadeusz
Ogińska, Halszka
Beldzik, Ewa
Domagalik, Aleksandra
Monograph
Monograph (alternative title)
Date
2024-01-08
Publisher
Journal title
Chronobiology International
Issue
2
Volume
41
Pages
Pages
201–212
ISSN
0742-0528
ISSN of series
Access date
Abstract PL
Abstract EN
Multiple aspects of brain functioning, including arousal, motivation, and cognitive performance, are governed by circadian rhythmicity. Although the recent rise in the use of magnetic resonance imaging (MRI) has enabled investigations into the macroscopic correlates of the diurnal brain processes, neuroanatomical studies are scarce. The current work investigated how time-of-day (TOD) impacts white (WM) and grey matter (GM) volumes using voxel-based morphometry (VBM) in a large dataset (N = 72) divided into two equal, comparable subsamples to assess the replicability of effects. Furthermore, we aimed to assess how the magnitude of these diurnal differences was related to actigraphy-derived indices of sleep health. The results extend the current knowledge by reporting that TOD is predominantly associated with regional WM volume decreases. Additionally, alongside corroborating previously observed volumetric GM decreases, we provide the first evidence for positive TOD effects. Higher replicability was observed for WM, with the only two replicated GM clusters being volumetric increases in the amygdala and hippocampus, and decreases in the retro-splenial cortex, with the latter more pronounced in individuals with shorter sleep times. These findings implicate the existence of region-specific mechanisms behind GM effects, which might be related to cognitive processes taking place during wakefulness and homeostatic sleep pressure.
Abstract other
Keywords PL
Keywords EN
Voxel-based morphometry
time-of-day
sleep length
grey matter
white matter
time-of-day
sleep length
grey matter
white matter
Keywords other
Exhibition title
Place of exhibition (institution)
Exhibition curator
Type
License type
Funder
Time range from
Time range to
Contact person name
Related publication
Related publication
Grant/project name
Wpływ pory dnia na neuronalne mechanizmy leżące u podłoża zniekształceń w pamięci krótkotrwałej wywołanych interferencją o charakterze leksykalnym i przestrzennym - badanie fMRI
Collections
Views
14Acquisition Date27.07.2024
Downloads
6Acquisition Date27.07.2024
Altmetrics©
Dimensions
Google Scholar
