Dataset of human-single neuron activity during a Sternberg working memory task

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cris.lastimport.scopus2025-04-06T03:12:00Z
dc.abstract.enWe present a dataset of 1809 single neurons recorded from the human medial temporal lobe (amygdala and hippocampus) and medial frontal lobe (anterior cingulate cortex, pre-supplementary motor area, ventral medial prefrontal cortex) across 41 sessions from 21 patients that underwent seizure monitoring with depth electrodes. Subjects performed a screening task (907 neurons) to identify images for which highly selective cells were present. Subjects then performed a working memory task (902 neurons), in which they were sequentially presented with 1–3 images for which highly selective cells were present and, following a maintenance period, were asked if the probe was identical to one of the maintained images. This Neurodata Without Borders formatted dataset includes spike times, extracellular spike waveforms, stimuli presented, behavior, electrode locations, and subject demographics. As validation, we replicate previous findings on the selectivity of concept cells and their persistent activity during working memory maintenance. This large dataset of rare human single-neuron recordings and behavior enables the investigation of the neural mechanisms of working memory in humans.
dc.affiliationWydział Psychologii
dc.affiliationWydział Psychologii w Warszawie
dc.affiliationInstytut Psychologii
dc.contributor.authorKyzar, Michael
dc.contributor.authorKamiński, Jan
dc.contributor.authorBrzezicka, Aneta
dc.contributor.authorReed, Chrystal M.
dc.contributor.authorChung, Jeffrey M.
dc.contributor.authorMamelak, Adam N.
dc.contributor.authorRutishauser, Ueli
dc.date.access2024-01-18
dc.date.accessioned2024-01-30T07:43:38Z
dc.date.available2024-01-30T07:43:38Z
dc.date.created2023
dc.date.issued2024-01-18
dc.description.abstract<jats:title>Abstract</jats:title><jats:p>We present a dataset of 1809 single neurons recorded from the human medial temporal lobe (amygdala and hippocampus) and medial frontal lobe (anterior cingulate cortex, pre-supplementary motor area, ventral medial prefrontal cortex) across 41 sessions from 21 patients that underwent seizure monitoring with depth electrodes. Subjects performed a screening task (907 neurons) to identify images for which highly selective cells were present. Subjects then performed a working memory task (902 neurons), in which they were sequentially presented with 1–3 images for which highly selective cells were present and, following a maintenance period, were asked if the probe was identical to one of the maintained images. This Neurodata Without Borders formatted dataset includes spike times, extracellular spike waveforms, stimuli presented, behavior, electrode locations, and subject demographics. As validation, we replicate previous findings on the selectivity of concept cells and their persistent activity during working memory maintenance. This large dataset of rare human single-neuron recordings and behavior enables the investigation of the neural mechanisms of working memory in humans.</jats:p>
dc.description.accesstimeat_publication
dc.description.issue1
dc.description.physical1-12
dc.description.versionfinal_published
dc.description.volume11
dc.identifier.doi10.1038/s41597-024-02943-8
dc.identifier.issn2052-4463
dc.identifier.urihttps://share.swps.edu.pl/handle/swps/427
dc.identifier.weblinkhttps://www.nature.com/articles/s41597-024-02943-8
dc.languageen
dc.pbn.affiliationpsychologia
dc.rightsCC-BY
dc.rights.questionYes_rights
dc.share.articleOPEN_JOURNAL
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dc.titleDataset of human-single neuron activity during a Sternberg working memory task
dc.title.journalScientific Data
dc.typeJournalArticle
dspace.entity.typeArticle